The cards have a new layout (although the cards backs remain unchanged, of course). Each card, both crypt and library, has an attribute bar along the left side where the attributes of the card (clan, discipline, cost, etc.) go. The red capacity circle remains in the lower-right corner, however.
The card-type-specific backgrounds have changed as well, both for crypt cards and for library cards.
The icons for blood cost and pool cost have also been updated. If a card costs blood, the amount is shown in a red drop (left). If a card costs pool, the amount is shown in a white diamond with a vampiric skull (right). In both cases the icon appears in the lower left corner of the card.